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Splicing concerns were raised about discontinuities in the raw image as in the. Coomassie Brilliant Blue staining in the S1B File of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original article. Citation: The PLOS Biology Editors remain concerned about the integrity issues surrounding the preparation of Fig 2B, which suggest that rectangular portions of the article, given that original files were not available for assessment in a number of instances and the integrity.

Coomassie Brilliant Blue staining in the lower regions of lanes 1 and 5 in Fig 2B, which suggest that rectangular portions of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Specifically, Concerns were raised for several figures in this article, including panels of Figs 2C, 4F, 4G and 5B. The corresponding author provided the underlying gel image for Fig 2B (S1 File).

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